manifest {
  name = 'bedtools/bedtools_multicov'
  mainScript = 'main.nf'
  nextflowVersion = '!>=20.12.1-edge'
  version = 'main'
  description = 'Count sequence coverage for multiple BAM files at specific genomic loci.\n\nbedtools multicov counts the number of alignments from multiple BAM files that overlap \neach interval in a BED/GFF/VCF file. For each genomic interval, it reports the coverage \nfrom each BAM file in additional columns, making it ideal for comparing coverage across \nmultiple samples or conditions.\n\nThis tool is commonly used for:\n- Multi-sample coverage analysis across specific regions\n- Comparing read depths between different samples\n- Quality control of sequencing experiments\n- Preparing coverage data for differential analysis\n- Generating coverage matrices for downstream analysis\n'
  author = 'Robrecht Cannoodt'
}

process.container = 'nextflow/bash:latest'

// detect tempdir
tempDir = java.nio.file.Paths.get(
  System.getenv('NXF_TEMP') ?:
    System.getenv('VIASH_TEMP') ?: 
    System.getenv('TEMPDIR') ?: 
    System.getenv('TMPDIR') ?: 
    '/tmp'
).toAbsolutePath()

profiles {
  no_publish {
    process {
      withName: '.*' {
        publishDir = [
          enabled: false
        ]
      }
    }
  }
  mount_temp {
    docker.temp            = tempDir
    podman.temp            = tempDir
    charliecloud.temp      = tempDir
  }
  docker {
    docker.enabled         = true
    // docker.userEmulation   = true
    singularity.enabled    = false
    podman.enabled         = false
    shifter.enabled        = false
    charliecloud.enabled   = false
  }
  singularity {
    singularity.enabled    = true
    singularity.autoMounts = true
    docker.enabled         = false
    podman.enabled         = false
    shifter.enabled        = false
    charliecloud.enabled   = false
  }
  podman {
    podman.enabled         = true
    docker.enabled         = false
    singularity.enabled    = false
    shifter.enabled        = false
    charliecloud.enabled   = false
  }
  shifter {
    shifter.enabled        = true
    docker.enabled         = false
    singularity.enabled    = false
    podman.enabled         = false
    charliecloud.enabled   = false
  }
  charliecloud {
    charliecloud.enabled   = true
    docker.enabled         = false
    singularity.enabled    = false
    podman.enabled         = false
    shifter.enabled        = false
  }
}

process{
  withLabel: mem1gb { memory = 1000000000.B }
  withLabel: mem2gb { memory = 2000000000.B }
  withLabel: mem5gb { memory = 5000000000.B }
  withLabel: mem10gb { memory = 10000000000.B }
  withLabel: mem20gb { memory = 20000000000.B }
  withLabel: mem50gb { memory = 50000000000.B }
  withLabel: mem100gb { memory = 100000000000.B }
  withLabel: mem200gb { memory = 200000000000.B }
  withLabel: mem500gb { memory = 500000000000.B }
  withLabel: mem1tb { memory = 1000000000000.B }
  withLabel: mem2tb { memory = 2000000000000.B }
  withLabel: mem5tb { memory = 5000000000000.B }
  withLabel: mem10tb { memory = 10000000000000.B }
  withLabel: mem20tb { memory = 20000000000000.B }
  withLabel: mem50tb { memory = 50000000000000.B }
  withLabel: mem100tb { memory = 100000000000000.B }
  withLabel: mem200tb { memory = 200000000000000.B }
  withLabel: mem500tb { memory = 500000000000000.B }
  withLabel: mem1gib { memory = 1073741824.B }
  withLabel: mem2gib { memory = 2147483648.B }
  withLabel: mem4gib { memory = 4294967296.B }
  withLabel: mem8gib { memory = 8589934592.B }
  withLabel: mem16gib { memory = 17179869184.B }
  withLabel: mem32gib { memory = 34359738368.B }
  withLabel: mem64gib { memory = 68719476736.B }
  withLabel: mem128gib { memory = 137438953472.B }
  withLabel: mem256gib { memory = 274877906944.B }
  withLabel: mem512gib { memory = 549755813888.B }
  withLabel: mem1tib { memory = 1099511627776.B }
  withLabel: mem2tib { memory = 2199023255552.B }
  withLabel: mem4tib { memory = 4398046511104.B }
  withLabel: mem8tib { memory = 8796093022208.B }
  withLabel: mem16tib { memory = 17592186044416.B }
  withLabel: mem32tib { memory = 35184372088832.B }
  withLabel: mem64tib { memory = 70368744177664.B }
  withLabel: mem128tib { memory = 140737488355328.B }
  withLabel: mem256tib { memory = 281474976710656.B }
  withLabel: mem512tib { memory = 562949953421312.B }
  withLabel: cpu1 { cpus = 1 }
  withLabel: cpu2 { cpus = 2 }
  withLabel: cpu5 { cpus = 5 }
  withLabel: cpu10 { cpus = 10 }
  withLabel: cpu20 { cpus = 20 }
  withLabel: cpu50 { cpus = 50 }
  withLabel: cpu100 { cpus = 100 }
  withLabel: cpu200 { cpus = 200 }
  withLabel: cpu500 { cpus = 500 }
  withLabel: cpu1000 { cpus = 1000 }
}


