#!/usr/bin/env bash

# filter_with_scrublet v3.0.0
# 
# This wrapper script is auto-generated by viash 0.9.4 and is thus a derivative
# work thereof. This software comes with ABSOLUTELY NO WARRANTY from Data
# Intuitive.
# 
# The component may contain files which fall under a different license. The
# authors of this component should specify the license in the header of such
# files, or include a separate license file detailing the licenses of all included
# files.
# 
# Component authors:
#  * Dries De Maeyer (contributor)
#  * Robrecht Cannoodt (maintainer, contributor)

set -e

if [ -z "$VIASH_TEMP" ]; then
  VIASH_TEMP=${VIASH_TEMP:-$VIASH_TMPDIR}
  VIASH_TEMP=${VIASH_TEMP:-$VIASH_TEMPDIR}
  VIASH_TEMP=${VIASH_TEMP:-$VIASH_TMP}
  VIASH_TEMP=${VIASH_TEMP:-$TMPDIR}
  VIASH_TEMP=${VIASH_TEMP:-$TMP}
  VIASH_TEMP=${VIASH_TEMP:-$TEMPDIR}
  VIASH_TEMP=${VIASH_TEMP:-$TEMP}
  VIASH_TEMP=${VIASH_TEMP:-/tmp}
fi

# define helper functions
# ViashQuote: put quotes around non flag values
# $1     : unquoted string
# return : possibly quoted string
# examples:
#   ViashQuote --foo      # returns --foo
#   ViashQuote bar        # returns 'bar'
#   Viashquote --foo=bar  # returns --foo='bar'
function ViashQuote {
  if [[ "$1" =~ ^-+[a-zA-Z0-9_\-]+=.+$ ]]; then
    echo "$1" | sed "s#=\(.*\)#='\1'#"
  elif [[ "$1" =~ ^-+[a-zA-Z0-9_\-]+$ ]]; then
    echo "$1"
  else
    echo "'$1'"
  fi
}
# ViashRemoveFlags: Remove leading flag
# $1     : string with a possible leading flag
# return : string without possible leading flag
# examples:
#   ViashRemoveFlags --foo=bar  # returns bar
function ViashRemoveFlags {
  echo "$1" | sed 's/^--*[a-zA-Z0-9_\-]*=//'
}
# ViashSourceDir: return the path of a bash file, following symlinks
# usage   : ViashSourceDir ${BASH_SOURCE[0]}
# $1      : Should always be set to ${BASH_SOURCE[0]}
# returns : The absolute path of the bash file
function ViashSourceDir {
  local source="$1"
  while [ -h "$source" ]; do
    local dir="$( cd -P "$( dirname "$source" )" >/dev/null 2>&1 && pwd )"
    source="$(readlink "$source")"
    [[ $source != /* ]] && source="$dir/$source"
  done
  cd -P "$( dirname "$source" )" >/dev/null 2>&1 && pwd
}
# ViashFindTargetDir: return the path of the '.build.yaml' file, following symlinks
# usage   : ViashFindTargetDir 'ScriptPath'
# $1      : The location from where to start the upward search
# returns : The absolute path of the '.build.yaml' file
function ViashFindTargetDir {
  local source="$1"
  while [[ "$source" != "" && ! -e "$source/.build.yaml" ]]; do
    source=${source%/*}
  done
  echo $source
}
# see https://en.wikipedia.org/wiki/Syslog#Severity_level
VIASH_LOGCODE_EMERGENCY=0
VIASH_LOGCODE_ALERT=1
VIASH_LOGCODE_CRITICAL=2
VIASH_LOGCODE_ERROR=3
VIASH_LOGCODE_WARNING=4
VIASH_LOGCODE_NOTICE=5
VIASH_LOGCODE_INFO=6
VIASH_LOGCODE_DEBUG=7
VIASH_VERBOSITY=$VIASH_LOGCODE_NOTICE

# ViashLog: Log events depending on the verbosity level
# usage: ViashLog 1 alert Oh no something went wrong!
# $1: required verbosity level
# $2: display tag
# $3+: messages to display
# stdout: Your input, prepended by '[$2] '.
function ViashLog {
  local required_level="$1"
  local display_tag="$2"
  shift 2
  if [ $VIASH_VERBOSITY -ge $required_level ]; then
    >&2 echo "[$display_tag]" "$@"
  fi
}

# ViashEmergency: log events when the system is unstable
# usage: ViashEmergency Oh no something went wrong.
# stdout: Your input, prepended by '[emergency] '.
function ViashEmergency {
  ViashLog $VIASH_LOGCODE_EMERGENCY emergency "$@"
}

# ViashAlert: log events when actions must be taken immediately (e.g. corrupted system database)
# usage: ViashAlert Oh no something went wrong.
# stdout: Your input, prepended by '[alert] '.
function ViashAlert {
  ViashLog $VIASH_LOGCODE_ALERT alert "$@"
}

# ViashCritical: log events when a critical condition occurs
# usage: ViashCritical Oh no something went wrong.
# stdout: Your input, prepended by '[critical] '.
function ViashCritical {
  ViashLog $VIASH_LOGCODE_CRITICAL critical "$@"
}

# ViashError: log events when an error condition occurs
# usage: ViashError Oh no something went wrong.
# stdout: Your input, prepended by '[error] '.
function ViashError {
  ViashLog $VIASH_LOGCODE_ERROR error "$@"
}

# ViashWarning: log potentially abnormal events
# usage: ViashWarning Something may have gone wrong.
# stdout: Your input, prepended by '[warning] '.
function ViashWarning {
  ViashLog $VIASH_LOGCODE_WARNING warning "$@"
}

# ViashNotice: log significant but normal events
# usage: ViashNotice This just happened.
# stdout: Your input, prepended by '[notice] '.
function ViashNotice {
  ViashLog $VIASH_LOGCODE_NOTICE notice "$@"
}

# ViashInfo: log normal events
# usage: ViashInfo This just happened.
# stdout: Your input, prepended by '[info] '.
function ViashInfo {
  ViashLog $VIASH_LOGCODE_INFO info "$@"
}

# ViashDebug: log all events, for debugging purposes
# usage: ViashDebug This just happened.
# stdout: Your input, prepended by '[debug] '.
function ViashDebug {
  ViashLog $VIASH_LOGCODE_DEBUG debug "$@"
}

# find source folder of this component
VIASH_META_RESOURCES_DIR=`ViashSourceDir ${BASH_SOURCE[0]}`

# find the root of the built components & dependencies
VIASH_TARGET_DIR=`ViashFindTargetDir $VIASH_META_RESOURCES_DIR`

# define meta fields
VIASH_META_NAME="filter_with_scrublet"
VIASH_META_FUNCTIONALITY_NAME="filter_with_scrublet"
VIASH_META_EXECUTABLE="$VIASH_META_RESOURCES_DIR/$VIASH_META_NAME"
VIASH_META_CONFIG="$VIASH_META_RESOURCES_DIR/.config.vsh.yaml"
VIASH_META_TEMP_DIR="$VIASH_TEMP"



# initialise variables
VIASH_MODE='run'
VIASH_ENGINE_ID='docker'

######## Helper functions for setting up Docker images for viash ########
# expects: ViashDockerBuild

# ViashDockerInstallationCheck: check whether Docker is installed correctly
#
# examples:
#   ViashDockerInstallationCheck
function ViashDockerInstallationCheck {
  ViashDebug "Checking whether Docker is installed"
  if [ ! command -v docker &> /dev/null ]; then
    ViashCritical "Docker doesn't seem to be installed. See 'https://docs.docker.com/get-docker/' for instructions."
    exit 1
  fi

  ViashDebug "Checking whether the Docker daemon is running"
  local save=$-; set +e
  local docker_version=$(docker version --format '{{.Client.APIVersion}}' 2> /dev/null)
  local out=$?
  [[ $save =~ e ]] && set -e
  if [ $out -ne 0 ]; then
    ViashCritical "Docker daemon does not seem to be running. Try one of the following:"
    ViashCritical "- Try running 'dockerd' in the command line"
    ViashCritical "- See https://docs.docker.com/config/daemon/"
    exit 1
  fi
}

# ViashDockerRemoteTagCheck: check whether a Docker image is available 
# on a remote. Assumes `docker login` has been performed, if relevant.
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# exit code $?        : whether or not the image was found
# examples:
#   ViashDockerRemoteTagCheck python:latest
#   echo $?                                     # returns '0'
#   ViashDockerRemoteTagCheck sdaizudceahifu
#   echo $?                                     # returns '1'
function ViashDockerRemoteTagCheck {
  docker manifest inspect $1 > /dev/null 2> /dev/null
}

# ViashDockerLocalTagCheck: check whether a Docker image is available locally
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# exit code $?        : whether or not the image was found
# examples:
#   docker pull python:latest
#   ViashDockerLocalTagCheck python:latest
#   echo $?                                     # returns '0'
#   ViashDockerLocalTagCheck sdaizudceahifu
#   echo $?                                     # returns '1'
function ViashDockerLocalTagCheck {
  [ -n "$(docker images -q $1)" ]
}

# ViashDockerPull: pull a Docker image
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# exit code $?        : whether or not the image was found
# examples:
#   ViashDockerPull python:latest
#   echo $?                                     # returns '0'
#   ViashDockerPull sdaizudceahifu
#   echo $?                                     # returns '1'
function ViashDockerPull {
  ViashNotice "Checking if Docker image is available at '$1'"
  if [ $VIASH_VERBOSITY -ge $VIASH_LOGCODE_INFO ]; then
    docker pull $1 && return 0 || return 1
  else
    local save=$-; set +e
    docker pull $1 2> /dev/null > /dev/null
    local out=$?
    [[ $save =~ e ]] && set -e
    if [ $out -ne 0 ]; then
      ViashWarning "Could not pull from '$1'. Docker image doesn't exist or is not accessible."
    fi
    return $out
  fi
}

# ViashDockerPush: push a Docker image
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# exit code $?        : whether or not the image was found
# examples:
#   ViashDockerPush python:latest
#   echo $?                                     # returns '0'
#   ViashDockerPush sdaizudceahifu
#   echo $?                                     # returns '1'
function ViashDockerPush {
  ViashNotice "Pushing image to '$1'"
  local save=$-; set +e
  local out
  if [ $VIASH_VERBOSITY -ge $VIASH_LOGCODE_INFO ]; then
    docker push $1
    out=$?
  else
    docker push $1 2> /dev/null > /dev/null
    out=$?
  fi
  [[ $save =~ e ]] && set -e
  if [ $out -eq 0 ]; then
    ViashNotice "Container '$1' push succeeded."
  else
    ViashError "Container '$1' push errored. You might not be logged in or have the necessary permissions."
  fi
  return $out
}

# ViashDockerPullElseBuild: pull a Docker image, else build it
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# ViashDockerBuild    : a Bash function which builds a docker image, takes image identifier as argument.
# examples:
#   ViashDockerPullElseBuild mynewcomponent
function ViashDockerPullElseBuild {
  local save=$-; set +e
  ViashDockerPull $1
  local out=$?
  [[ $save =~ e ]] && set -e
  if [ $out -ne 0 ]; then
    ViashDockerBuild $@
  fi
}

# ViashDockerSetup: create a Docker image, according to specified docker setup strategy
#
# $1          : image identifier with format `[registry/]image[:tag]`
# $2          : docker setup strategy, see DockerSetupStrategy.scala
# examples:
#   ViashDockerSetup mynewcomponent alwaysbuild
function ViashDockerSetup {
  local image_id="$1"
  local setup_strategy="$2"
  if [ "$setup_strategy" == "alwaysbuild" -o "$setup_strategy" == "build" -o "$setup_strategy" == "b" ]; then
    ViashDockerBuild $image_id --no-cache $(ViashDockerBuildArgs "$engine_id")
  elif [ "$setup_strategy" == "alwayspull" -o "$setup_strategy" == "pull" -o "$setup_strategy" == "p" ]; then
    ViashDockerPull $image_id
  elif [ "$setup_strategy" == "alwayspullelsebuild" -o "$setup_strategy" == "pullelsebuild" ]; then
    ViashDockerPullElseBuild $image_id --no-cache $(ViashDockerBuildArgs "$engine_id")
  elif [ "$setup_strategy" == "alwayspullelsecachedbuild" -o "$setup_strategy" == "pullelsecachedbuild" ]; then
    ViashDockerPullElseBuild $image_id $(ViashDockerBuildArgs "$engine_id")
  elif [ "$setup_strategy" == "alwayscachedbuild" -o "$setup_strategy" == "cachedbuild" -o "$setup_strategy" == "cb" ]; then
    ViashDockerBuild $image_id $(ViashDockerBuildArgs "$engine_id")
  elif [[ "$setup_strategy" =~ ^ifneedbe ]]; then
    local save=$-; set +e
    ViashDockerLocalTagCheck $image_id
    local outCheck=$?
    [[ $save =~ e ]] && set -e
    if [ $outCheck -eq 0 ]; then
      ViashInfo "Image $image_id already exists"
    elif [ "$setup_strategy" == "ifneedbebuild" ]; then
      ViashDockerBuild $image_id --no-cache $(ViashDockerBuildArgs "$engine_id")
    elif [ "$setup_strategy" == "ifneedbecachedbuild" ]; then
      ViashDockerBuild $image_id $(ViashDockerBuildArgs "$engine_id")
    elif [ "$setup_strategy" == "ifneedbepull" ]; then
      ViashDockerPull $image_id
    elif [ "$setup_strategy" == "ifneedbepullelsebuild" ]; then
      ViashDockerPullElseBuild $image_id --no-cache $(ViashDockerBuildArgs "$engine_id")
    elif [ "$setup_strategy" == "ifneedbepullelsecachedbuild" ]; then
      ViashDockerPullElseBuild $image_id $(ViashDockerBuildArgs "$engine_id")
    else
      ViashError "Unrecognised Docker strategy: $setup_strategy"
      exit 1
    fi
  elif [ "$setup_strategy" == "push" -o "$setup_strategy" == "forcepush" -o "$setup_strategy" == "alwayspush" ]; then
    ViashDockerPush "$image_id"
  elif [ "$setup_strategy" == "pushifnotpresent" -o "$setup_strategy" == "gentlepush" -o "$setup_strategy" == "maybepush" ]; then
    local save=$-; set +e
    ViashDockerRemoteTagCheck $image_id
    local outCheck=$?
    [[ $save =~ e ]] && set -e
    if [ $outCheck -eq 0 ]; then
      ViashNotice "Container '$image_id' exists, doing nothing."
    else
      ViashNotice "Container '$image_id' does not yet exist."
      ViashDockerPush "$image_id"
    fi
  elif [ "$setup_strategy" == "donothing" -o "$setup_strategy" == "meh" ]; then
    ViashNotice "Skipping setup."
  else
    ViashError "Unrecognised Docker strategy: $setup_strategy"
    exit 1
  fi
}

# ViashDockerCheckCommands: Check whether a docker container has the required commands
#
# $1                  : image identifier with format `[registry/]image[:tag]`
# $@                  : commands to verify being present
# examples:
#   ViashDockerCheckCommands bash:4.0 bash ps foo
function ViashDockerCheckCommands {
  local image_id="$1"
  shift 1
  local commands="$@"
  local save=$-; set +e
  local missing # mark 'missing' as local in advance, otherwise the exit code of the command will be missing and always be '0'
  missing=$(docker run --rm --entrypoint=sh "$image_id" -c "for command in $commands; do command -v \$command >/dev/null 2>&1; if [ \$? -ne 0 ]; then echo \$command; exit 1; fi; done")
  local outCheck=$?
  [[ $save =~ e ]] && set -e
  if [ $outCheck -ne 0 ]; then
  	ViashError "Docker container '$image_id' does not contain command '$missing'."
  	exit 1
  fi
}

# ViashDockerBuild: build a docker image
# $1                               : image identifier with format `[registry/]image[:tag]`
# $...                             : additional arguments to pass to docker build
# $VIASH_META_TEMP_DIR             : temporary directory to store dockerfile & optional resources in
# $VIASH_META_NAME                 : name of the component
# $VIASH_META_RESOURCES_DIR        : directory containing the resources
# $VIASH_VERBOSITY                 : verbosity level
# exit code $?                     : whether or not the image was built successfully
function ViashDockerBuild {
  local image_id="$1"
  shift 1

  # create temporary directory to store dockerfile & optional resources in
  local tmpdir=$(mktemp -d "$VIASH_META_TEMP_DIR/dockerbuild-$VIASH_META_NAME-XXXXXX")
  local dockerfile="$tmpdir/Dockerfile"
  function clean_up {
    rm -rf "$tmpdir"
  }
  trap clean_up EXIT

  # store dockerfile and resources
  ViashDockerfile "$VIASH_ENGINE_ID" > "$dockerfile"

  # generate the build command
  local docker_build_cmd="docker build -t '$image_id' $@ '$VIASH_META_RESOURCES_DIR' -f '$dockerfile'"

  # build the container
  ViashNotice "Building container '$image_id' with Dockerfile"
  ViashInfo "$docker_build_cmd"
  local save=$-; set +e
  if [ $VIASH_VERBOSITY -ge $VIASH_LOGCODE_INFO ]; then
    eval $docker_build_cmd
  else
    eval $docker_build_cmd &> "$tmpdir/docker_build.log"
  fi

  # check exit code
  local out=$?
  [[ $save =~ e ]] && set -e
  if [ $out -ne 0 ]; then
    ViashError "Error occurred while building container '$image_id'"
    if [ $VIASH_VERBOSITY -lt $VIASH_LOGCODE_INFO ]; then
      ViashError "Transcript: --------------------------------"
      cat "$tmpdir/docker_build.log"
      ViashError "End of transcript --------------------------"
    fi
    exit 1
  fi
}

######## End of helper functions for setting up Docker images for viash ########

# ViashDockerFile: print the dockerfile to stdout
# $1    : engine identifier
# return : dockerfile required to run this component
# examples:
#   ViashDockerFile
function ViashDockerfile {
  local engine_id="$1"

  if [[ "$engine_id" == "docker" ]]; then
    cat << 'VIASHDOCKER'
FROM python:3.10-slim
ENTRYPOINT []
RUN apt-get update && \
  DEBIAN_FRONTEND=noninteractive apt-get install -y procps build-essential && \
  rm -rf /var/lib/apt/lists/*

RUN pip install --upgrade pip && \
  pip install --upgrade --no-cache-dir "anndata~=0.11.1" "mudata~=0.3.1" "scanpy~=1.10.4" "scrublet" "annoy==1.17.3" && \
  python -c 'exec("try:\n  import awkward\nexcept ModuleNotFoundError:\n  exit(0)\nelse:  exit(1)")'

LABEL org.opencontainers.image.authors="Dries De Maeyer, Robrecht Cannoodt"
LABEL org.opencontainers.image.description="Companion container for running component filter filter_with_scrublet"
LABEL org.opencontainers.image.created="2025-08-22T15:44:06Z"
LABEL org.opencontainers.image.source="https://github.com/openpipelines-bio/openpipeline"
LABEL org.opencontainers.image.revision="e92e56b49125af8ef2ebb11586191a6cbf9a8457"
LABEL org.opencontainers.image.version="v3.0.0"

VIASHDOCKER
  fi
}

# ViashDockerBuildArgs: return the arguments to pass to docker build
# $1    : engine identifier
# return : arguments to pass to docker build
function ViashDockerBuildArgs {
  local engine_id="$1"

  if [[ "$engine_id" == "docker" ]]; then
    echo ""
  fi
}

# ViashAbsolutePath: generate absolute path from relative path
# borrowed from https://stackoverflow.com/a/21951256
# $1     : relative filename
# return : absolute path
# examples:
#   ViashAbsolutePath some_file.txt   # returns /path/to/some_file.txt
#   ViashAbsolutePath /foo/bar/..     # returns /foo
function ViashAbsolutePath {
  local thePath
  local parr
  local outp
  local len
  if [[ ! "$1" =~ ^/ ]]; then
    thePath="$PWD/$1"
  else
    thePath="$1"
  fi
  echo "$thePath" | (
    IFS=/
    read -a parr
    declare -a outp
    for i in "${parr[@]}"; do
      case "$i" in
      ''|.) continue ;;
      ..)
        len=${#outp[@]}
        if ((len==0)); then
          continue
        else
          unset outp[$((len-1))]
        fi
        ;;
      *)
        len=${#outp[@]}
        outp[$len]="$i"
      ;;
      esac
    done
    echo /"${outp[*]}"
  )
}
# ViashDockerAutodetectMount: auto configuring docker mounts from parameters
# $1                             : The parameter value
# returns                        : New parameter
# $VIASH_DIRECTORY_MOUNTS        : Added another parameter to be passed to docker
# $VIASH_DOCKER_AUTOMOUNT_PREFIX : The prefix to be used for the automounts
# examples:
#   ViashDockerAutodetectMount /path/to/bar      # returns '/viash_automount/path/to/bar'
#   ViashDockerAutodetectMountArg /path/to/bar   # returns '--volume="/path/to:/viash_automount/path/to"'
function ViashDockerAutodetectMount {
  local abs_path=$(ViashAbsolutePath "$1")
  local mount_source
  local base_name
  if [ -d "$abs_path" ]; then
    mount_source="$abs_path"
    base_name=""
  else
    mount_source=`dirname "$abs_path"`
    base_name=`basename "$abs_path"`
  fi
  local mount_target="$VIASH_DOCKER_AUTOMOUNT_PREFIX$mount_source"
  if [ -z "$base_name" ]; then
    echo "$mount_target"
  else
    echo "$mount_target/$base_name"
  fi
}
function ViashDockerAutodetectMountArg {
  local abs_path=$(ViashAbsolutePath "$1")
  local mount_source
  local base_name
  if [ -d "$abs_path" ]; then
    mount_source="$abs_path"
    base_name=""
  else
    mount_source=`dirname "$abs_path"`
    base_name=`basename "$abs_path"`
  fi
  local mount_target="$VIASH_DOCKER_AUTOMOUNT_PREFIX$mount_source"
  ViashDebug "ViashDockerAutodetectMountArg $1 -> $mount_source -> $mount_target"
  echo "--volume=\"$mount_source:$mount_target\""
}
function ViashDockerStripAutomount {
  local abs_path=$(ViashAbsolutePath "$1")
  echo "${abs_path#$VIASH_DOCKER_AUTOMOUNT_PREFIX}"
}
# initialise variables
VIASH_DIRECTORY_MOUNTS=()

# configure default docker automount prefix if it is unset
if [ -z "${VIASH_DOCKER_AUTOMOUNT_PREFIX+x}" ]; then
  VIASH_DOCKER_AUTOMOUNT_PREFIX="/viash_automount"
fi

# initialise docker variables
VIASH_DOCKER_RUN_ARGS=(-i --rm --env NUMBA_CACHE_DIR=/tmp)


# ViashHelp: Display helpful explanation about this executable
function ViashHelp {
  echo "filter_with_scrublet v3.0.0"
  echo ""
  echo "Doublet detection using the Scrublet method (Wolock, Lopez and Klein, 2019)."
  echo "The method tests for potential doublets by using the expression profiles of"
  echo "cells to generate synthetic potential doubles which are tested against cells."
  echo "The method returns a \"doublet score\" on which it calls for potential doublets."
  echo ""
  echo "For the source code please visit https://github.com/AllonKleinLab/scrublet."
  echo ""
  echo "For 10x we expect the doublet rates to be:"
  echo "  Multiplet Rate (%) - # of Cells Loaded - # of Cells Recovered"
  echo "  ~0.4% ~800 ~500"
  echo "  ~0.8% ~1,600 ~1,000"
  echo "  ~1.6% ~3,200 ~2,000"
  echo "  ~2.3% ~4,800 ~3,000"
  echo "  ~3.1% ~6,400 ~4,000"
  echo "  ~3.9% ~8,000 ~5,000"
  echo "  ~4.6% ~9,600 ~6,000"
  echo "  ~5.4% ~11,200 ~7,000"
  echo "  ~6.1% ~12,800 ~8,000"
  echo "  ~6.9% ~14,400 ~9,000"
  echo "  ~7.6% ~16,000 ~10,000"
  echo ""
  echo "Arguments:"
  echo "    --input"
  echo "        type: file, required parameter, file must exist"
  echo "        example: input.h5mu"
  echo "        Input h5mu file"
  echo ""
  echo "    --modality"
  echo "        type: string"
  echo "        default: rna"
  echo "        Which modality from the input MuData file to process."
  echo ""
  echo "    --layer"
  echo "        type: string"
  echo "        Input layer to use as data for calculating doublets. .X is used not"
  echo "        specified."
  echo ""
  echo "    --output"
  echo "        type: file, output, file must exist"
  echo "        example: output.h5mu"
  echo "        Output h5mu file."
  echo ""
  echo "    --obs_name_filter"
  echo "        type: string"
  echo "        default: filter_with_scrublet"
  echo "        In which .obs slot to store a boolean array corresponding to which"
  echo "        observations should be filtered out."
  echo ""
  echo "    --do_subset"
  echo "        type: boolean_true"
  echo "        Whether to subset before storing the output."
  echo ""
  echo "    --obs_name_doublet_score"
  echo "        type: string"
  echo "        default: scrublet_doublet_score"
  echo "        Name of the doublet scores column in the obs slot of the returned"
  echo "        object."
  echo ""
  echo "    --expected_doublet_rate"
  echo "        type: double"
  echo "        min: 0.0"
  echo "        max: 1.0"
  echo "        The estimated fraction of doublets as from the experimental setup."
  echo ""
  echo "    --stdev_doublet_rate"
  echo "        type: double"
  echo "        min: 0.0"
  echo "        Uncertainty in the expected doublet rate."
  echo ""
  echo "    --n_neighbors"
  echo "        type: integer"
  echo "        min: 0"
  echo "        Number of neighbors used to construct the KNN classifier of observed"
  echo "        transcriptomes"
  echo "        and simulated doublets."
  echo ""
  echo "    --sim_doublet_ratio"
  echo "        type: double"
  echo "        min: 0.0"
  echo "        Number of doublets to simulate relative to the number of observed"
  echo "        transcriptomes."
  echo ""
  echo "    --min_counts"
  echo "        type: integer"
  echo "        default: 2"
  echo "        The number of minimal UMI counts per cell that have to be present for"
  echo "        initial cell detection."
  echo ""
  echo "    --min_cells"
  echo "        type: integer"
  echo "        default: 3"
  echo "        The number of cells in which UMIs for a gene were detected."
  echo ""
  echo "    --min_gene_variablity_percent"
  echo "        type: double"
  echo "        default: 85.0"
  echo "        Used for gene filtering prior to PCA. Keep the most highly variable"
  echo "        genes (in the top min_gene_variability_pctl percentile), as measured by"
  echo "        the v-statistic [Klein et al., Cell 2015]."
  echo ""
  echo "    --num_pca_components"
  echo "        type: integer"
  echo "        default: 30"
  echo "        Number of principal components to use during PCA dimensionality"
  echo "        reduction."
  echo ""
  echo "    --distance_metric"
  echo "        type: string"
  echo "        default: euclidean"
  echo "        The distance metric used for computing similarities."
  echo ""
  echo "    --allow_automatic_threshold_detection_fail"
  echo "        type: boolean_true"
  echo "        When scrublet fails to automatically determine the double score"
  echo "        threshold,"
  echo "        allow the component to continue and set the output columns to NA."
  echo ""
  echo "    --output_compression"
  echo "        type: string"
  echo "        example: gzip"
  echo "        choices: [ gzip, lzf ]"
  echo "        Compression format to use for the output AnnData and/or Mudata objects."
  echo "        By default no compression is applied."
  echo ""
  echo "Viash built in Computational Requirements:"
  echo "    ---cpus=INT"
  echo "        Number of CPUs to use"
  echo "    ---memory=STRING"
  echo "        Amount of memory to use. Examples: 4GB, 3MiB."
  echo ""
  echo "Viash built in Docker:"
  echo "    ---setup=STRATEGY"
  echo "        Setup the docker container. Options are: alwaysbuild, alwayscachedbuild, ifneedbebuild, ifneedbecachedbuild, alwayspull, alwayspullelsebuild, alwayspullelsecachedbuild, ifneedbepull, ifneedbepullelsebuild, ifneedbepullelsecachedbuild, push, pushifnotpresent, donothing."
  echo "        Default: ifneedbepullelsecachedbuild"
  echo "    ---dockerfile"
  echo "        Print the dockerfile to stdout."
  echo "    ---docker_run_args=ARG"
  echo "        Provide runtime arguments to Docker. See the documentation on \`docker run\` for more information."
  echo "    ---docker_image_id"
  echo "        Print the docker image id to stdout."
  echo "    ---debug"
  echo "        Enter the docker container for debugging purposes."
  echo ""
  echo "Viash built in Engines:"
  echo "    ---engine=ENGINE_ID"
  echo "        Specify the engine to use. Options are: docker, native."
  echo "        Default: docker"
}

# initialise array
VIASH_POSITIONAL_ARGS=''

while [[ $# -gt 0 ]]; do
    case "$1" in
        -h|--help)
            ViashHelp
            exit
            ;;
        ---v|---verbose)
            let "VIASH_VERBOSITY=VIASH_VERBOSITY+1"
            shift 1
            ;;
        ---verbosity)
            VIASH_VERBOSITY="$2"
            shift 2
            ;;
        ---verbosity=*)
            VIASH_VERBOSITY="$(ViashRemoveFlags "$1")"
            shift 1
            ;;
        --version)
            echo "filter_with_scrublet v3.0.0"
            exit
            ;;
        --input)
            [ -n "$VIASH_PAR_INPUT" ] && ViashError Bad arguments for option \'--input\': \'$VIASH_PAR_INPUT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_INPUT="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --input. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --input=*)
            [ -n "$VIASH_PAR_INPUT" ] && ViashError Bad arguments for option \'--input=*\': \'$VIASH_PAR_INPUT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_INPUT=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --modality)
            [ -n "$VIASH_PAR_MODALITY" ] && ViashError Bad arguments for option \'--modality\': \'$VIASH_PAR_MODALITY\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MODALITY="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --modality. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --modality=*)
            [ -n "$VIASH_PAR_MODALITY" ] && ViashError Bad arguments for option \'--modality=*\': \'$VIASH_PAR_MODALITY\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MODALITY=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --layer)
            [ -n "$VIASH_PAR_LAYER" ] && ViashError Bad arguments for option \'--layer\': \'$VIASH_PAR_LAYER\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_LAYER="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --layer. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --layer=*)
            [ -n "$VIASH_PAR_LAYER" ] && ViashError Bad arguments for option \'--layer=*\': \'$VIASH_PAR_LAYER\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_LAYER=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --output)
            [ -n "$VIASH_PAR_OUTPUT" ] && ViashError Bad arguments for option \'--output\': \'$VIASH_PAR_OUTPUT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OUTPUT="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --output. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --output=*)
            [ -n "$VIASH_PAR_OUTPUT" ] && ViashError Bad arguments for option \'--output=*\': \'$VIASH_PAR_OUTPUT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OUTPUT=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --obs_name_filter)
            [ -n "$VIASH_PAR_OBS_NAME_FILTER" ] && ViashError Bad arguments for option \'--obs_name_filter\': \'$VIASH_PAR_OBS_NAME_FILTER\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OBS_NAME_FILTER="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --obs_name_filter. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --obs_name_filter=*)
            [ -n "$VIASH_PAR_OBS_NAME_FILTER" ] && ViashError Bad arguments for option \'--obs_name_filter=*\': \'$VIASH_PAR_OBS_NAME_FILTER\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OBS_NAME_FILTER=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --do_subset)
            [ -n "$VIASH_PAR_DO_SUBSET" ] && ViashError Bad arguments for option \'--do_subset\': \'$VIASH_PAR_DO_SUBSET\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_DO_SUBSET=true
            shift 1
            ;;
        --obs_name_doublet_score)
            [ -n "$VIASH_PAR_OBS_NAME_DOUBLET_SCORE" ] && ViashError Bad arguments for option \'--obs_name_doublet_score\': \'$VIASH_PAR_OBS_NAME_DOUBLET_SCORE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OBS_NAME_DOUBLET_SCORE="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --obs_name_doublet_score. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --obs_name_doublet_score=*)
            [ -n "$VIASH_PAR_OBS_NAME_DOUBLET_SCORE" ] && ViashError Bad arguments for option \'--obs_name_doublet_score=*\': \'$VIASH_PAR_OBS_NAME_DOUBLET_SCORE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OBS_NAME_DOUBLET_SCORE=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --expected_doublet_rate)
            [ -n "$VIASH_PAR_EXPECTED_DOUBLET_RATE" ] && ViashError Bad arguments for option \'--expected_doublet_rate\': \'$VIASH_PAR_EXPECTED_DOUBLET_RATE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_EXPECTED_DOUBLET_RATE="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --expected_doublet_rate. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --expected_doublet_rate=*)
            [ -n "$VIASH_PAR_EXPECTED_DOUBLET_RATE" ] && ViashError Bad arguments for option \'--expected_doublet_rate=*\': \'$VIASH_PAR_EXPECTED_DOUBLET_RATE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_EXPECTED_DOUBLET_RATE=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --stdev_doublet_rate)
            [ -n "$VIASH_PAR_STDEV_DOUBLET_RATE" ] && ViashError Bad arguments for option \'--stdev_doublet_rate\': \'$VIASH_PAR_STDEV_DOUBLET_RATE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_STDEV_DOUBLET_RATE="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --stdev_doublet_rate. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --stdev_doublet_rate=*)
            [ -n "$VIASH_PAR_STDEV_DOUBLET_RATE" ] && ViashError Bad arguments for option \'--stdev_doublet_rate=*\': \'$VIASH_PAR_STDEV_DOUBLET_RATE\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_STDEV_DOUBLET_RATE=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --n_neighbors)
            [ -n "$VIASH_PAR_N_NEIGHBORS" ] && ViashError Bad arguments for option \'--n_neighbors\': \'$VIASH_PAR_N_NEIGHBORS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_N_NEIGHBORS="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --n_neighbors. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --n_neighbors=*)
            [ -n "$VIASH_PAR_N_NEIGHBORS" ] && ViashError Bad arguments for option \'--n_neighbors=*\': \'$VIASH_PAR_N_NEIGHBORS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_N_NEIGHBORS=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --sim_doublet_ratio)
            [ -n "$VIASH_PAR_SIM_DOUBLET_RATIO" ] && ViashError Bad arguments for option \'--sim_doublet_ratio\': \'$VIASH_PAR_SIM_DOUBLET_RATIO\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_SIM_DOUBLET_RATIO="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --sim_doublet_ratio. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --sim_doublet_ratio=*)
            [ -n "$VIASH_PAR_SIM_DOUBLET_RATIO" ] && ViashError Bad arguments for option \'--sim_doublet_ratio=*\': \'$VIASH_PAR_SIM_DOUBLET_RATIO\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_SIM_DOUBLET_RATIO=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --min_counts)
            [ -n "$VIASH_PAR_MIN_COUNTS" ] && ViashError Bad arguments for option \'--min_counts\': \'$VIASH_PAR_MIN_COUNTS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_COUNTS="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --min_counts. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --min_counts=*)
            [ -n "$VIASH_PAR_MIN_COUNTS" ] && ViashError Bad arguments for option \'--min_counts=*\': \'$VIASH_PAR_MIN_COUNTS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_COUNTS=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --min_cells)
            [ -n "$VIASH_PAR_MIN_CELLS" ] && ViashError Bad arguments for option \'--min_cells\': \'$VIASH_PAR_MIN_CELLS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_CELLS="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --min_cells. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --min_cells=*)
            [ -n "$VIASH_PAR_MIN_CELLS" ] && ViashError Bad arguments for option \'--min_cells=*\': \'$VIASH_PAR_MIN_CELLS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_CELLS=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --min_gene_variablity_percent)
            [ -n "$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT" ] && ViashError Bad arguments for option \'--min_gene_variablity_percent\': \'$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --min_gene_variablity_percent. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --min_gene_variablity_percent=*)
            [ -n "$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT" ] && ViashError Bad arguments for option \'--min_gene_variablity_percent=*\': \'$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --num_pca_components)
            [ -n "$VIASH_PAR_NUM_PCA_COMPONENTS" ] && ViashError Bad arguments for option \'--num_pca_components\': \'$VIASH_PAR_NUM_PCA_COMPONENTS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_NUM_PCA_COMPONENTS="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --num_pca_components. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --num_pca_components=*)
            [ -n "$VIASH_PAR_NUM_PCA_COMPONENTS" ] && ViashError Bad arguments for option \'--num_pca_components=*\': \'$VIASH_PAR_NUM_PCA_COMPONENTS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_NUM_PCA_COMPONENTS=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --distance_metric)
            [ -n "$VIASH_PAR_DISTANCE_METRIC" ] && ViashError Bad arguments for option \'--distance_metric\': \'$VIASH_PAR_DISTANCE_METRIC\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_DISTANCE_METRIC="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --distance_metric. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --distance_metric=*)
            [ -n "$VIASH_PAR_DISTANCE_METRIC" ] && ViashError Bad arguments for option \'--distance_metric=*\': \'$VIASH_PAR_DISTANCE_METRIC\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_DISTANCE_METRIC=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        --allow_automatic_threshold_detection_fail)
            [ -n "$VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL" ] && ViashError Bad arguments for option \'--allow_automatic_threshold_detection_fail\': \'$VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL=true
            shift 1
            ;;
        --output_compression)
            [ -n "$VIASH_PAR_OUTPUT_COMPRESSION" ] && ViashError Bad arguments for option \'--output_compression\': \'$VIASH_PAR_OUTPUT_COMPRESSION\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OUTPUT_COMPRESSION="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to --output_compression. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        --output_compression=*)
            [ -n "$VIASH_PAR_OUTPUT_COMPRESSION" ] && ViashError Bad arguments for option \'--output_compression=*\': \'$VIASH_PAR_OUTPUT_COMPRESSION\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_PAR_OUTPUT_COMPRESSION=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        ---engine)
            VIASH_ENGINE_ID="$2"
            shift 2
            ;;
        ---engine=*)
            VIASH_ENGINE_ID="$(ViashRemoveFlags "$1")"
            shift 1
            ;;
        ---setup)
            VIASH_MODE='setup'
            VIASH_SETUP_STRATEGY="$2"
            shift 2
            ;;
        ---setup=*)
            VIASH_MODE='setup'
            VIASH_SETUP_STRATEGY="$(ViashRemoveFlags "$1")"
            shift 1
            ;;
        ---dockerfile)
            VIASH_MODE='dockerfile'
            shift 1
            ;;
        ---docker_run_args)
            VIASH_DOCKER_RUN_ARGS+=("$2")
            shift 2
            ;;
        ---docker_run_args=*)
            VIASH_DOCKER_RUN_ARGS+=("$(ViashRemoveFlags "$1")")
            shift 1
            ;;
        ---docker_image_id)
            VIASH_MODE='docker_image_id'
            shift 1
            ;;
        ---debug)
            VIASH_MODE='debug'
            shift 1
            ;;
        ---cpus)
            [ -n "$VIASH_META_CPUS" ] && ViashError Bad arguments for option \'---cpus\': \'$VIASH_META_CPUS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_META_CPUS="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to ---cpus. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        ---cpus=*)
            [ -n "$VIASH_META_CPUS" ] && ViashError Bad arguments for option \'---cpus=*\': \'$VIASH_META_CPUS\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_META_CPUS=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        ---memory)
            [ -n "$VIASH_META_MEMORY" ] && ViashError Bad arguments for option \'---memory\': \'$VIASH_META_MEMORY\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_META_MEMORY="$2"
            [ $# -lt 2 ] && ViashError Not enough arguments passed to ---memory. Use "--help" to get more information on the parameters. && exit 1
            shift 2
            ;;
        ---memory=*)
            [ -n "$VIASH_META_MEMORY" ] && ViashError Bad arguments for option \'---memory=*\': \'$VIASH_META_MEMORY\' \& \'$2\' - you should provide exactly one argument for this option. && exit 1
            VIASH_META_MEMORY=$(ViashRemoveFlags "$1")
            shift 1
            ;;
        *)  # positional arg or unknown option
            # since the positional args will be eval'd, can we always quote, instead of using ViashQuote
            VIASH_POSITIONAL_ARGS="$VIASH_POSITIONAL_ARGS '$1'"
            [[ $1 == -* ]] && ViashWarning $1 looks like a parameter but is not a defined parameter and will instead be treated as a positional argument. Use "--help" to get more information on the parameters.
            shift # past argument
            ;;
    esac
done

# parse positional parameters
eval set -- $VIASH_POSITIONAL_ARGS


if   [ "$VIASH_ENGINE_ID" == "native" ]  ; then
  VIASH_ENGINE_TYPE='native'
elif   [ "$VIASH_ENGINE_ID" == "docker" ]  ; then
  VIASH_ENGINE_TYPE='docker'
else
  ViashError "Engine '$VIASH_ENGINE_ID' is not recognized. Options are: docker, native."
  exit 1
fi

if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  # check if docker is installed properly
  ViashDockerInstallationCheck

  # determine docker image id
  if [[ "$VIASH_ENGINE_ID" == 'docker' ]]; then
    VIASH_DOCKER_IMAGE_ID='images.viash-hub.com/vsh/openpipeline/filter/filter_with_scrublet:v3.0.0'
  fi

  # print dockerfile
  if [ "$VIASH_MODE" == "dockerfile" ]; then
    ViashDockerfile "$VIASH_ENGINE_ID"
    exit 0

  elif [ "$VIASH_MODE" == "docker_image_id" ]; then
    echo "$VIASH_DOCKER_IMAGE_ID"
    exit 0
  
  # enter docker container
  elif [[ "$VIASH_MODE" == "debug" ]]; then
    VIASH_CMD="docker run --entrypoint=bash ${VIASH_DOCKER_RUN_ARGS[@]} -v '$(pwd)':/pwd --workdir /pwd -t $VIASH_DOCKER_IMAGE_ID"
    ViashNotice "+ $VIASH_CMD"
    eval $VIASH_CMD
    exit 

  # build docker image
  elif [ "$VIASH_MODE" == "setup" ]; then
    ViashDockerSetup "$VIASH_DOCKER_IMAGE_ID" "$VIASH_SETUP_STRATEGY"
    ViashDockerCheckCommands "$VIASH_DOCKER_IMAGE_ID" 'bash'
    exit 0
  fi

  # check if docker image exists
  ViashDockerSetup "$VIASH_DOCKER_IMAGE_ID" ifneedbepullelsecachedbuild
  ViashDockerCheckCommands "$VIASH_DOCKER_IMAGE_ID" 'bash'
fi

# setting computational defaults

# helper function for parsing memory strings
function ViashMemoryAsBytes {
  local memory=`echo "$1" | tr '[:upper:]' '[:lower:]' | tr -d '[:space:]'`
  local memory_regex='^([0-9]+)([kmgtp]i?b?|b)$'
  if [[ $memory =~ $memory_regex ]]; then
    local number=${memory/[^0-9]*/}
    local symbol=${memory/*[0-9]/}
    
    case $symbol in
      b)      memory_b=$number ;;
      kb|k)   memory_b=$(( $number * 1000 )) ;;
      mb|m)   memory_b=$(( $number * 1000 * 1000 )) ;;
      gb|g)   memory_b=$(( $number * 1000 * 1000 * 1000 )) ;;
      tb|t)   memory_b=$(( $number * 1000 * 1000 * 1000 * 1000 )) ;;
      pb|p)   memory_b=$(( $number * 1000 * 1000 * 1000 * 1000 * 1000 )) ;;
      kib|ki)   memory_b=$(( $number * 1024 )) ;;
      mib|mi)   memory_b=$(( $number * 1024 * 1024 )) ;;
      gib|gi)   memory_b=$(( $number * 1024 * 1024 * 1024 )) ;;
      tib|ti)   memory_b=$(( $number * 1024 * 1024 * 1024 * 1024 )) ;;
      pib|pi)   memory_b=$(( $number * 1024 * 1024 * 1024 * 1024 * 1024 )) ;;
    esac
    echo "$memory_b"
  fi
}
# compute memory in different units
if [ ! -z ${VIASH_META_MEMORY+x} ]; then
  VIASH_META_MEMORY_B=`ViashMemoryAsBytes $VIASH_META_MEMORY`
  # do not define other variables if memory_b is an empty string
  if [ ! -z "$VIASH_META_MEMORY_B" ]; then
    VIASH_META_MEMORY_KB=$(( ($VIASH_META_MEMORY_B+999) / 1000 ))
    VIASH_META_MEMORY_MB=$(( ($VIASH_META_MEMORY_KB+999) / 1000 ))
    VIASH_META_MEMORY_GB=$(( ($VIASH_META_MEMORY_MB+999) / 1000 ))
    VIASH_META_MEMORY_TB=$(( ($VIASH_META_MEMORY_GB+999) / 1000 ))
    VIASH_META_MEMORY_PB=$(( ($VIASH_META_MEMORY_TB+999) / 1000 ))
    VIASH_META_MEMORY_KIB=$(( ($VIASH_META_MEMORY_B+1023) / 1024 ))
    VIASH_META_MEMORY_MIB=$(( ($VIASH_META_MEMORY_KIB+1023) / 1024 ))
    VIASH_META_MEMORY_GIB=$(( ($VIASH_META_MEMORY_MIB+1023) / 1024 ))
    VIASH_META_MEMORY_TIB=$(( ($VIASH_META_MEMORY_GIB+1023) / 1024 ))
    VIASH_META_MEMORY_PIB=$(( ($VIASH_META_MEMORY_TIB+1023) / 1024 ))
  else
    # unset memory if string is empty
    unset $VIASH_META_MEMORY_B
  fi
fi
# unset nproc if string is empty
if [ -z "$VIASH_META_CPUS" ]; then
  unset $VIASH_META_CPUS
fi


# check whether required parameters exist
if [ -z ${VIASH_PAR_INPUT+x} ]; then
  ViashError '--input' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_NAME+x} ]; then
  ViashError 'name' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_FUNCTIONALITY_NAME+x} ]; then
  ViashError 'functionality_name' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_RESOURCES_DIR+x} ]; then
  ViashError 'resources_dir' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_EXECUTABLE+x} ]; then
  ViashError 'executable' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_CONFIG+x} ]; then
  ViashError 'config' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi
if [ -z ${VIASH_META_TEMP_DIR+x} ]; then
  ViashError 'temp_dir' is a required argument. Use "--help" to get more information on the parameters.
  exit 1
fi

# filling in defaults
if [ -z ${VIASH_PAR_MODALITY+x} ]; then
  VIASH_PAR_MODALITY="rna"
fi
if [ -z ${VIASH_PAR_OBS_NAME_FILTER+x} ]; then
  VIASH_PAR_OBS_NAME_FILTER="filter_with_scrublet"
fi
if [ -z ${VIASH_PAR_DO_SUBSET+x} ]; then
  VIASH_PAR_DO_SUBSET="false"
fi
if [ -z ${VIASH_PAR_OBS_NAME_DOUBLET_SCORE+x} ]; then
  VIASH_PAR_OBS_NAME_DOUBLET_SCORE="scrublet_doublet_score"
fi
if [ -z ${VIASH_PAR_MIN_COUNTS+x} ]; then
  VIASH_PAR_MIN_COUNTS="2"
fi
if [ -z ${VIASH_PAR_MIN_CELLS+x} ]; then
  VIASH_PAR_MIN_CELLS="3"
fi
if [ -z ${VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT+x} ]; then
  VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT="85.0"
fi
if [ -z ${VIASH_PAR_NUM_PCA_COMPONENTS+x} ]; then
  VIASH_PAR_NUM_PCA_COMPONENTS="30"
fi
if [ -z ${VIASH_PAR_DISTANCE_METRIC+x} ]; then
  VIASH_PAR_DISTANCE_METRIC="euclidean"
fi
if [ -z ${VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL+x} ]; then
  VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL="false"
fi

# check whether required files exist
if [ ! -z "$VIASH_PAR_INPUT" ] && [ ! -e "$VIASH_PAR_INPUT" ]; then
  ViashError "Input file '$VIASH_PAR_INPUT' does not exist."
  exit 1
fi

# check whether parameters values are of the right type
if [[ -n "$VIASH_PAR_DO_SUBSET" ]]; then
  if ! [[ "$VIASH_PAR_DO_SUBSET" =~ ^(true|True|TRUE|false|False|FALSE|yes|Yes|YES|no|No|NO)$ ]]; then
    ViashError '--do_subset' has to be a boolean_true. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_EXPECTED_DOUBLET_RATE" ]]; then
  if ! [[ "$VIASH_PAR_EXPECTED_DOUBLET_RATE" =~ ^[-+]?(\.[0-9]+|[0-9]+(\.[0-9]*)?)([eE][-+]?[0-9]+)?$ ]]; then
    ViashError '--expected_doublet_rate' has to be a double. Use "--help" to get more information on the parameters.
    exit 1
  fi
  if command -v bc &> /dev/null; then
    if ! [[ `echo $VIASH_PAR_EXPECTED_DOUBLET_RATE '>=' 0.0 | bc` -eq 1 ]]; then
      ViashError '--expected_doublet_rate' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  elif command -v awk &> /dev/null; then
    if ! [[ `awk -v n1=$VIASH_PAR_EXPECTED_DOUBLET_RATE -v n2=0.0 'BEGIN { print (n1 >= n2) ? "1" : "0" }'` -eq 1 ]]; then
      ViashError '--expected_doublet_rate' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  else
    ViashWarning '--expected_doublet_rate' specifies a minimum value but the value was not verified as neither \'bc\' or \`awk\` are present on the system.
  fi
  if command -v bc &> /dev/null; then
    if ! [[ `echo $VIASH_PAR_EXPECTED_DOUBLET_RATE '<=' 1.0 | bc` -eq 1 ]]; then
      ViashError '--expected_doublet_rate' has to be less than or equal to 1.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  elif command -v awk &> /dev/null; then
    if ! [[ `awk -v n1=$VIASH_PAR_EXPECTED_DOUBLET_RATE -v n2=1.0 'BEGIN { print (n1 <= n2) ? "1" : "0" }'` -eq 1 ]]; then
      ViashError '--expected_doublet_rate' has be less than or equal to 1.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  else
    ViashWarning '--expected_doublet_rate' specifies a maximum value but the value was not verified as neither \'bc\' or \'awk\' are present on the system.
  fi
fi
if [[ -n "$VIASH_PAR_STDEV_DOUBLET_RATE" ]]; then
  if ! [[ "$VIASH_PAR_STDEV_DOUBLET_RATE" =~ ^[-+]?(\.[0-9]+|[0-9]+(\.[0-9]*)?)([eE][-+]?[0-9]+)?$ ]]; then
    ViashError '--stdev_doublet_rate' has to be a double. Use "--help" to get more information on the parameters.
    exit 1
  fi
  if command -v bc &> /dev/null; then
    if ! [[ `echo $VIASH_PAR_STDEV_DOUBLET_RATE '>=' 0.0 | bc` -eq 1 ]]; then
      ViashError '--stdev_doublet_rate' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  elif command -v awk &> /dev/null; then
    if ! [[ `awk -v n1=$VIASH_PAR_STDEV_DOUBLET_RATE -v n2=0.0 'BEGIN { print (n1 >= n2) ? "1" : "0" }'` -eq 1 ]]; then
      ViashError '--stdev_doublet_rate' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  else
    ViashWarning '--stdev_doublet_rate' specifies a minimum value but the value was not verified as neither \'bc\' or \`awk\` are present on the system.
  fi
fi
if [[ -n "$VIASH_PAR_N_NEIGHBORS" ]]; then
  if ! [[ "$VIASH_PAR_N_NEIGHBORS" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError '--n_neighbors' has to be an integer. Use "--help" to get more information on the parameters.
    exit 1
  fi
  if [[ $VIASH_PAR_N_NEIGHBORS -lt 0 ]]; then
    ViashError '--n_neighbors' has be more than or equal to 0. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_SIM_DOUBLET_RATIO" ]]; then
  if ! [[ "$VIASH_PAR_SIM_DOUBLET_RATIO" =~ ^[-+]?(\.[0-9]+|[0-9]+(\.[0-9]*)?)([eE][-+]?[0-9]+)?$ ]]; then
    ViashError '--sim_doublet_ratio' has to be a double. Use "--help" to get more information on the parameters.
    exit 1
  fi
  if command -v bc &> /dev/null; then
    if ! [[ `echo $VIASH_PAR_SIM_DOUBLET_RATIO '>=' 0.0 | bc` -eq 1 ]]; then
      ViashError '--sim_doublet_ratio' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  elif command -v awk &> /dev/null; then
    if ! [[ `awk -v n1=$VIASH_PAR_SIM_DOUBLET_RATIO -v n2=0.0 'BEGIN { print (n1 >= n2) ? "1" : "0" }'` -eq 1 ]]; then
      ViashError '--sim_doublet_ratio' has be more than or equal to 0.0. Use "--help" to get more information on the parameters.
      exit 1
    fi
  else
    ViashWarning '--sim_doublet_ratio' specifies a minimum value but the value was not verified as neither \'bc\' or \`awk\` are present on the system.
  fi
fi
if [[ -n "$VIASH_PAR_MIN_COUNTS" ]]; then
  if ! [[ "$VIASH_PAR_MIN_COUNTS" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError '--min_counts' has to be an integer. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_MIN_CELLS" ]]; then
  if ! [[ "$VIASH_PAR_MIN_CELLS" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError '--min_cells' has to be an integer. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT" ]]; then
  if ! [[ "$VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT" =~ ^[-+]?(\.[0-9]+|[0-9]+(\.[0-9]*)?)([eE][-+]?[0-9]+)?$ ]]; then
    ViashError '--min_gene_variablity_percent' has to be a double. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_NUM_PCA_COMPONENTS" ]]; then
  if ! [[ "$VIASH_PAR_NUM_PCA_COMPONENTS" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError '--num_pca_components' has to be an integer. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL" ]]; then
  if ! [[ "$VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL" =~ ^(true|True|TRUE|false|False|FALSE|yes|Yes|YES|no|No|NO)$ ]]; then
    ViashError '--allow_automatic_threshold_detection_fail' has to be a boolean_true. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_CPUS" ]]; then
  if ! [[ "$VIASH_META_CPUS" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'cpus' has to be an integer. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_B" ]]; then
  if ! [[ "$VIASH_META_MEMORY_B" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_b' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_KB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_KB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_kb' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_MB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_MB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_mb' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_GB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_GB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_gb' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_TB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_TB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_tb' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_PB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_PB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_pb' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_KIB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_KIB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_kib' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_MIB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_MIB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_mib' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_GIB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_GIB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_gib' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_TIB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_TIB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_tib' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi
if [[ -n "$VIASH_META_MEMORY_PIB" ]]; then
  if ! [[ "$VIASH_META_MEMORY_PIB" =~ ^[-+]?[0-9]+$ ]]; then
    ViashError 'memory_pib' has to be a long. Use "--help" to get more information on the parameters.
    exit 1
  fi
fi

# check whether value is belongs to a set of choices
if [ ! -z "$VIASH_PAR_OUTPUT_COMPRESSION" ]; then
  VIASH_PAR_OUTPUT_COMPRESSION_CHOICES=("gzip;lzf")
  IFS=';'
  set -f
  if ! [[ ";${VIASH_PAR_OUTPUT_COMPRESSION_CHOICES[*]};" =~ ";$VIASH_PAR_OUTPUT_COMPRESSION;" ]]; then
    ViashError '--output_compression' specified value of \'$VIASH_PAR_OUTPUT_COMPRESSION\' is not in the list of allowed values. Use "--help" to get more information on the parameters.
    exit 1
  fi
  set +f
  unset IFS
fi

# create parent directories of output files, if so desired
if [ ! -z "$VIASH_PAR_OUTPUT" ] && [ ! -d "$(dirname "$VIASH_PAR_OUTPUT")" ]; then
  mkdir -p "$(dirname "$VIASH_PAR_OUTPUT")"
fi

if  [ "$VIASH_ENGINE_ID" == "native" ]  ; then
  if [ "$VIASH_MODE" == "run" ]; then
    VIASH_CMD="bash"
  else
    ViashError "Engine '$VIASH_ENGINE_ID' does not support mode '$VIASH_MODE'."
    exit 1
  fi
fi

if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  # detect volumes from file arguments
  VIASH_CHOWN_VARS=()
if [ ! -z "$VIASH_PAR_INPUT" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_PAR_INPUT")" )
  VIASH_PAR_INPUT=$(ViashDockerAutodetectMount "$VIASH_PAR_INPUT")
fi
if [ ! -z "$VIASH_PAR_OUTPUT" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_PAR_OUTPUT")" )
  VIASH_PAR_OUTPUT=$(ViashDockerAutodetectMount "$VIASH_PAR_OUTPUT")
  VIASH_CHOWN_VARS+=( "$VIASH_PAR_OUTPUT" )
fi
if [ ! -z "$VIASH_META_RESOURCES_DIR" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_META_RESOURCES_DIR")" )
  VIASH_META_RESOURCES_DIR=$(ViashDockerAutodetectMount "$VIASH_META_RESOURCES_DIR")
fi
if [ ! -z "$VIASH_META_EXECUTABLE" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_META_EXECUTABLE")" )
  VIASH_META_EXECUTABLE=$(ViashDockerAutodetectMount "$VIASH_META_EXECUTABLE")
fi
if [ ! -z "$VIASH_META_CONFIG" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_META_CONFIG")" )
  VIASH_META_CONFIG=$(ViashDockerAutodetectMount "$VIASH_META_CONFIG")
fi
if [ ! -z "$VIASH_META_TEMP_DIR" ]; then
  VIASH_DIRECTORY_MOUNTS+=( "$(ViashDockerAutodetectMountArg "$VIASH_META_TEMP_DIR")" )
  VIASH_META_TEMP_DIR=$(ViashDockerAutodetectMount "$VIASH_META_TEMP_DIR")
fi
  
  # get unique mounts
  VIASH_UNIQUE_MOUNTS=($(for val in "${VIASH_DIRECTORY_MOUNTS[@]}"; do echo "$val"; done | sort -u))
fi

if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  # change file ownership
  function ViashPerformChown {
    if (( ${#VIASH_CHOWN_VARS[@]} )); then
      set +e
      VIASH_CMD="docker run --entrypoint=bash --rm ${VIASH_UNIQUE_MOUNTS[@]} $VIASH_DOCKER_IMAGE_ID -c 'chown $(id -u):$(id -g) --silent --recursive ${VIASH_CHOWN_VARS[@]}'"
      ViashDebug "+ $VIASH_CMD"
      eval $VIASH_CMD
      set -e
    fi
  }
  trap ViashPerformChown EXIT
fi

if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  # helper function for filling in extra docker args
  if [ ! -z "$VIASH_META_MEMORY_B" ]; then
    VIASH_DOCKER_RUN_ARGS+=("--memory=${VIASH_META_MEMORY_B}")
  fi
  if [ ! -z "$VIASH_META_CPUS" ]; then
    VIASH_DOCKER_RUN_ARGS+=("--cpus=${VIASH_META_CPUS}")
  fi
fi

if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  VIASH_CMD="docker run --entrypoint=bash ${VIASH_DOCKER_RUN_ARGS[@]} ${VIASH_UNIQUE_MOUNTS[@]} $VIASH_DOCKER_IMAGE_ID"
fi


# set dependency paths


ViashDebug "Running command: $(echo $VIASH_CMD)"
cat << VIASHEOF | eval $VIASH_CMD
set -e
tempscript=\$(mktemp "$VIASH_META_TEMP_DIR/viash-run-filter_with_scrublet-XXXXXX").py
function clean_up {
  rm "\$tempscript"
}
function interrupt {
  echo -e "\nCTRL-C Pressed..."
  exit 1
}
trap clean_up EXIT
trap interrupt INT SIGINT
cat > "\$tempscript" << 'VIASHMAIN'
import scrublet as scr
import mudata as mu
import numpy as np
import sys
import pandas as pd

### VIASH START
# The following code has been auto-generated by Viash.
par = {
  'input': $( if [ ! -z ${VIASH_PAR_INPUT+x} ]; then echo "r'${VIASH_PAR_INPUT//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'modality': $( if [ ! -z ${VIASH_PAR_MODALITY+x} ]; then echo "r'${VIASH_PAR_MODALITY//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'layer': $( if [ ! -z ${VIASH_PAR_LAYER+x} ]; then echo "r'${VIASH_PAR_LAYER//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'output': $( if [ ! -z ${VIASH_PAR_OUTPUT+x} ]; then echo "r'${VIASH_PAR_OUTPUT//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'obs_name_filter': $( if [ ! -z ${VIASH_PAR_OBS_NAME_FILTER+x} ]; then echo "r'${VIASH_PAR_OBS_NAME_FILTER//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'do_subset': $( if [ ! -z ${VIASH_PAR_DO_SUBSET+x} ]; then echo "r'${VIASH_PAR_DO_SUBSET//\'/\'\"\'\"r\'}'.lower() == 'true'"; else echo None; fi ),
  'obs_name_doublet_score': $( if [ ! -z ${VIASH_PAR_OBS_NAME_DOUBLET_SCORE+x} ]; then echo "r'${VIASH_PAR_OBS_NAME_DOUBLET_SCORE//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'expected_doublet_rate': $( if [ ! -z ${VIASH_PAR_EXPECTED_DOUBLET_RATE+x} ]; then echo "float(r'${VIASH_PAR_EXPECTED_DOUBLET_RATE//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'stdev_doublet_rate': $( if [ ! -z ${VIASH_PAR_STDEV_DOUBLET_RATE+x} ]; then echo "float(r'${VIASH_PAR_STDEV_DOUBLET_RATE//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'n_neighbors': $( if [ ! -z ${VIASH_PAR_N_NEIGHBORS+x} ]; then echo "int(r'${VIASH_PAR_N_NEIGHBORS//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'sim_doublet_ratio': $( if [ ! -z ${VIASH_PAR_SIM_DOUBLET_RATIO+x} ]; then echo "float(r'${VIASH_PAR_SIM_DOUBLET_RATIO//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'min_counts': $( if [ ! -z ${VIASH_PAR_MIN_COUNTS+x} ]; then echo "int(r'${VIASH_PAR_MIN_COUNTS//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'min_cells': $( if [ ! -z ${VIASH_PAR_MIN_CELLS+x} ]; then echo "int(r'${VIASH_PAR_MIN_CELLS//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'min_gene_variablity_percent': $( if [ ! -z ${VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT+x} ]; then echo "float(r'${VIASH_PAR_MIN_GENE_VARIABLITY_PERCENT//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'num_pca_components': $( if [ ! -z ${VIASH_PAR_NUM_PCA_COMPONENTS+x} ]; then echo "int(r'${VIASH_PAR_NUM_PCA_COMPONENTS//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'distance_metric': $( if [ ! -z ${VIASH_PAR_DISTANCE_METRIC+x} ]; then echo "r'${VIASH_PAR_DISTANCE_METRIC//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'allow_automatic_threshold_detection_fail': $( if [ ! -z ${VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL+x} ]; then echo "r'${VIASH_PAR_ALLOW_AUTOMATIC_THRESHOLD_DETECTION_FAIL//\'/\'\"\'\"r\'}'.lower() == 'true'"; else echo None; fi ),
  'output_compression': $( if [ ! -z ${VIASH_PAR_OUTPUT_COMPRESSION+x} ]; then echo "r'${VIASH_PAR_OUTPUT_COMPRESSION//\'/\'\"\'\"r\'}'"; else echo None; fi )
}
meta = {
  'name': $( if [ ! -z ${VIASH_META_NAME+x} ]; then echo "r'${VIASH_META_NAME//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'functionality_name': $( if [ ! -z ${VIASH_META_FUNCTIONALITY_NAME+x} ]; then echo "r'${VIASH_META_FUNCTIONALITY_NAME//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'resources_dir': $( if [ ! -z ${VIASH_META_RESOURCES_DIR+x} ]; then echo "r'${VIASH_META_RESOURCES_DIR//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'executable': $( if [ ! -z ${VIASH_META_EXECUTABLE+x} ]; then echo "r'${VIASH_META_EXECUTABLE//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'config': $( if [ ! -z ${VIASH_META_CONFIG+x} ]; then echo "r'${VIASH_META_CONFIG//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'temp_dir': $( if [ ! -z ${VIASH_META_TEMP_DIR+x} ]; then echo "r'${VIASH_META_TEMP_DIR//\'/\'\"\'\"r\'}'"; else echo None; fi ),
  'cpus': $( if [ ! -z ${VIASH_META_CPUS+x} ]; then echo "int(r'${VIASH_META_CPUS//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_b': $( if [ ! -z ${VIASH_META_MEMORY_B+x} ]; then echo "int(r'${VIASH_META_MEMORY_B//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_kb': $( if [ ! -z ${VIASH_META_MEMORY_KB+x} ]; then echo "int(r'${VIASH_META_MEMORY_KB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_mb': $( if [ ! -z ${VIASH_META_MEMORY_MB+x} ]; then echo "int(r'${VIASH_META_MEMORY_MB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_gb': $( if [ ! -z ${VIASH_META_MEMORY_GB+x} ]; then echo "int(r'${VIASH_META_MEMORY_GB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_tb': $( if [ ! -z ${VIASH_META_MEMORY_TB+x} ]; then echo "int(r'${VIASH_META_MEMORY_TB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_pb': $( if [ ! -z ${VIASH_META_MEMORY_PB+x} ]; then echo "int(r'${VIASH_META_MEMORY_PB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_kib': $( if [ ! -z ${VIASH_META_MEMORY_KIB+x} ]; then echo "int(r'${VIASH_META_MEMORY_KIB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_mib': $( if [ ! -z ${VIASH_META_MEMORY_MIB+x} ]; then echo "int(r'${VIASH_META_MEMORY_MIB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_gib': $( if [ ! -z ${VIASH_META_MEMORY_GIB+x} ]; then echo "int(r'${VIASH_META_MEMORY_GIB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_tib': $( if [ ! -z ${VIASH_META_MEMORY_TIB+x} ]; then echo "int(r'${VIASH_META_MEMORY_TIB//\'/\'\"\'\"r\'}')"; else echo None; fi ),
  'memory_pib': $( if [ ! -z ${VIASH_META_MEMORY_PIB+x} ]; then echo "int(r'${VIASH_META_MEMORY_PIB//\'/\'\"\'\"r\'}')"; else echo None; fi )
}
dep = {
  
}

### VIASH END

sys.path.append(meta["resources_dir"])
from setup_logger import setup_logger
from compress_h5mu import write_h5ad_to_h5mu_with_compression


logger = setup_logger()

logger.info("Reading %s, modality %s", par["input"], par["modality"])
data = mu.read_h5ad(par["input"], mod=par["modality"])

logger.info("Using layer '%s'.", "X" if not par["layer"] else par["layer"])
input_layer = data.X if not par["layer"] else data.layers[par["layer"]]

if 0 in input_layer.shape:
    raise ValueError(
        f"Modality {par['modality']} of input Mudata {par['input']} appears "
        f"to be empty (shape: {input_layer.shape})."
    )

logger.info("\\tRunning scrublet")
initializer_args = {
    arg: par[arg]
    for arg in (
        "expected_doublet_rate",
        "stdev_doublet_rate",
        "n_neighbors",
        "sim_doublet_ratio",
    )
    if par[arg] is not None
}
scrub = scr.Scrublet(input_layer, **initializer_args)

doublet_scores, predicted_doublets = scrub.scrub_doublets(
    min_counts=par["min_counts"],
    min_cells=par["min_cells"],
    min_gene_variability_pctl=par["min_gene_variablity_percent"],
    n_prin_comps=par["num_pca_components"],
    distance_metric=par["distance_metric"],
    use_approx_neighbors=False,
)

try:
    keep_cells = np.invert(predicted_doublets)
except TypeError:
    if par["allow_automatic_threshold_detection_fail"]:
        # Scrublet might not throw an error and return None if it fails to detect doublets...
        logger.info(
            "\\tScrublet could not automatically detect the doublet score threshold. Setting output columns to NA."
        )
        keep_cells = np.nan
        doublet_scores = np.nan
    else:
        raise RuntimeError(
            "Scrublet could not automatically detect the doublet score threshold. "
            "--allow_automatic_threshold_detection_fail can be used to ignore this failure "
            "and set the corresponding output columns to NA."
        )

logger.info("\\tStoring output into .obs")
if par["obs_name_doublet_score"] is not None:
    data.obs[par["obs_name_doublet_score"]] = doublet_scores
    data.obs[par["obs_name_doublet_score"]] = data.obs[
        par["obs_name_doublet_score"]
    ].astype("float64")
if par["obs_name_filter"] is not None:
    data.obs[par["obs_name_filter"]] = keep_cells
    data.obs[par["obs_name_filter"]] = data.obs[par["obs_name_filter"]].astype(
        pd.BooleanDtype()
    )

if par["do_subset"]:
    if pd.api.types.is_scalar(keep_cells) and pd.isna(keep_cells):
        logger.warning("Not subsetting beacuse doublets were not predicted")
    else:
        data = data[keep_cells, :]

logger.info(
    "Writing h5mu to %s, with compression %s", par["output"], par["output_compression"]
)
write_h5ad_to_h5mu_with_compression(
    par["output"], par["input"], par["modality"], data, par["output_compression"]
)
VIASHMAIN
python -B "\$tempscript" &
wait "\$!"

VIASHEOF


if [[ "$VIASH_ENGINE_TYPE" == "docker" ]]; then
  # strip viash automount from file paths
  
  if [ ! -z "$VIASH_PAR_INPUT" ]; then
    VIASH_PAR_INPUT=$(ViashDockerStripAutomount "$VIASH_PAR_INPUT")
  fi
  if [ ! -z "$VIASH_PAR_OUTPUT" ]; then
    VIASH_PAR_OUTPUT=$(ViashDockerStripAutomount "$VIASH_PAR_OUTPUT")
  fi
  if [ ! -z "$VIASH_META_RESOURCES_DIR" ]; then
    VIASH_META_RESOURCES_DIR=$(ViashDockerStripAutomount "$VIASH_META_RESOURCES_DIR")
  fi
  if [ ! -z "$VIASH_META_EXECUTABLE" ]; then
    VIASH_META_EXECUTABLE=$(ViashDockerStripAutomount "$VIASH_META_EXECUTABLE")
  fi
  if [ ! -z "$VIASH_META_CONFIG" ]; then
    VIASH_META_CONFIG=$(ViashDockerStripAutomount "$VIASH_META_CONFIG")
  fi
  if [ ! -z "$VIASH_META_TEMP_DIR" ]; then
    VIASH_META_TEMP_DIR=$(ViashDockerStripAutomount "$VIASH_META_TEMP_DIR")
  fi
fi


# check whether required files exist
if [ ! -z "$VIASH_PAR_OUTPUT" ] && [ ! -e "$VIASH_PAR_OUTPUT" ]; then
  ViashError "Output file '$VIASH_PAR_OUTPUT' does not exist."
  exit 1
fi


exit 0
