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CI cd5554d22f Build branch main with version main (173327cc)
Build pipeline: vsh-ci-build-template-k4qzr

Source commit: 173327cc56

Source message: Cellranger multi conversion: fix combined AB + CB probe experiments (#1062)
2025-08-22 08:50:18 +00:00

32 lines
1.1 KiB
Python

def subset_vars(adata, subset_col):
"""Subset AnnData object on highly variable genes
Parameters
----------
adata : AnnData
Annotated data object
subset_col : str
Name of the boolean column in `adata.var` that contains the information if features should be used or not
Returns
-------
AnnData
Copy of `adata` with subsetted features
"""
if subset_col not in adata.var.columns:
raise ValueError(
f"Requested to use .var column '{subset_col}' as a selection of genes, but the column is not available."
)
if adata.var[subset_col].dtype == "boolean":
assert adata.var[subset_col].isna().sum() == 0, (
f"The .var column `{subset_col}` contains NaN values. Can not subset data."
)
adata.var[subset_col] = adata.var[subset_col].astype("bool")
assert adata.var[subset_col].dtype == "bool", (
f"Expected dtype of .var column '{subset_col}' to be `bool`, but found {adata.var[subset_col].dtype}. Can not subset data."
)
return adata[:, adata.var[subset_col]].copy()